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Continuous renal replacement therapy in children after cardiac surgery

Tuesday, July 23, 2013

Submitted by

Source

Source Name: Journal of Thoracic and Cardioavascular Surgery

Source URL: http://www.jtcvsonline.org/article/S0022-5223%2813%2900197-9/abstract

Author(s)

MJ Santiago, J Lopez-Herce, J Urbano, MJ Solana, J del Castillo, A Sanchez, JM Bellon.

This prospective observational study compared outcomes in children undergoing cardiac surgery and requiring continuous renal replacement therapy (CRRT) to other critically ill children also requiring CRRT. Of 1650 patients undergoing cardiac surgery, 5% required CRRT and 80% of those patients had multiorgan failure. 43% of those requiring CRRT after cardiac surgery died compared to 29% of other children requiring CRRT. In multivariable analysis, the only factor related to an increased risk of mortality on CRRT was hypotension at the time of instituting CRRT.