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Haytham Elgharably

Haytham Elgharably, M.D.

Cleveland Clinic Foundation
9500 Euclid Avenue/Main Campus (Desk J4-1)
Cleveland, OH  44195
United States
216 213 4679
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Role: 
Surgeon - Cardiothoracic

Background

Zagazig university medical school (M.D. 2004)
Zagazig university hospitals Internship (2005 - 2006)
Zagazig university hospitals Internship (2006-2007)
National Heart Institute CTS Residency (2007-2010)
Cleveland Clinic Foundation CTS Fellowship (2012-2013)
Cleveland Clinic Foundation Integrated Thoracic Surgery Residency (2013 - 2019)
Staff Surgeon at Cleveland Clinic (2019-present)
Surgical Director of Endocarditis Center at Cleveland Clinic (2023-present)

Other Interests

Lung Transplantation
Infection Endocarditis
Right heart failure
Reoperation
Pulmonary endarterectomy
Radiation heart disease

Research

 ADDIN EN.CITE.DATA  ADDIN EN.CITE.DATA  ADDIN EN.CITE.DATA  ADDIN EN.CITE.DATA 1-65

 

1.            Awad AK, Sayed A, Elbadawy MA, Ahmed A, Ming Wang TK, Elgharably H. Concomitant tricuspid valve repair for mild-moderate tricuspid regurgitation patients undergoing mitral valve surgery? A meta-analysis and meta-regression. J Cardiovasc Surg (Torino). 2023;64:657-667. doi: 10.23736/s0021-9509.23.12760-1

2.            Awad H, Abas M, Elgharably H, Tripathi R, Theofilos T, Bhandary S, Sai-Sudhakar C, Sen CK, Roy S. Endogenous opioids in wound-site neutrophils of sternotomy patients. PLoS One. 2012;7:e47569. doi: 10.1371/journal.pone.0047569

3.            Awad H, Elgharably H, Buohliqah L, Dimitrova GT, Go MR. Reversal of paralysis and visceral ischemia after thoracic aortic ligation for infection via extra anatomic ascending aorta to infarenal aorta bypass graft. J Cardiothorac Surg. 2014;9:142. doi: 10.1186/s13019-014-0142-4

4.            Awad H, Elgharably H, Popovich PG. Role of induced hypothermia in thoracoabdominal aortic aneurysm surgery. Ther Hypothermia Temp Manag. 2012;2:119-137. doi: 10.1089/ther.2012.0009

5.            Barron JO, Jain N, Mubashir M, Elgharably H, Raymond DP, Schraufnagel DP. Novel Repair of Clamshell Thoracotomy Sternal Dehiscence after Lung Transplant: A Case Report. J Chest Surg. 2024;57:213-216. doi: 10.5090/jcs.23.099

6.            Cikach F, Sale S, Roselli EE, Pettersson G, Elgharably H. Re-operation for a detached left coronary button from an aortic root conduit causing a large retro-sternal pseudoaneurysm. Multimed Man Cardiothorac Surg. 2023;2023. doi: 10.1510/mmcts.2023.026

7.            Elgharably H, Ayyat KS, Okamoto T, Thuita L, Unai S, Bribriesco AC, Yun JJ, Johnston DR, Ahmad U, Murthy SC, et al. Evolution of Recipient Characteristics Over 3 Decades and Impact on Survival After Lung Transplantation. Transplantation. 2021;105:e387-e394. doi: 10.1097/tp.0000000000003756

8.            Elgharably H, Bakaeen FG, Pettersson GB. Third time mitral valve replacement-lessons learned. J Card Surg. 2017;32:571-573. doi: 10.1111/jocs.13198

9.            Elgharably H, Blackstone EH, Navia JL. Reply. Ann Thorac Surg. 2018;105:986. doi: 10.1016/j.athoracsur.2017.10.010

10.         Elgharably H, De Villiers P, Navia JL. Early mitral bioprosthetic failure secondary to strut entrapment by suture loop causing severe valve incompetence. J Card Surg. 2017;32:199-200. doi: 10.1111/jocs.13100

11.         Elgharably H, Gamaleldin M, Ayyat KS, Zaki A, Hodges K, Kindzelski B, Sharma S, Hassab T, Yongue C, Serna S, et al. Serious Gastrointestinal Complications After Cardiac Surgery and Associated Mortality. Ann Thorac Surg. 2021;112:1266-1274. doi: 10.1016/j.athoracsur.2020.09.034

12.         Elgharably H, Ganesh K, Dickerson J, Khanna S, Abas M, Ghatak PD, Dixit S, Bergdall V, Roy S, Sen CK. A modified collagen gel dressing promotes angiogenesis in a preclinical swine model of chronic ischemic wounds. Wound Repair Regen. 2014;22:720-729. doi: 10.1111/wrr.12229

13.         Elgharably H, Hakim AH, Unai S, Hussain ST, Shrestha NK, Gordon S, Rodriguez L, Gillinov AM, Svensson LG, Navia JL. The incorporated aortomitral homograft for double-valve endocarditis: the 'hemi-Commando' procedure. Early and mid-term outcomes. Eur J Cardiothorac Surg. 2018;53:1055-1061. doi: 10.1093/ejcts/ezx439

14.         Elgharably H, Halbreiner MS, Shoenhagen P, Navia JL. Repair of left ventricular pseudoaneurysm with the triple patch technique (Empanada Patch). Interact Cardiovasc Thorac Surg. 2016;22:116-117. doi: 10.1093/icvts/ivv288

15.         Elgharably H, Harb SC, Kapadia S, Svensson LG, Navia JL. Transcatheter innovations in tricuspid regurgitation: Navigate. Prog Cardiovasc Dis. 2019;62:493-495. doi: 10.1016/j.pcad.2019.11.004

16.         Elgharably H, Hussain ST, Shrestha NK, Blackstone EH, Pettersson GB. Current Hypotheses in Cardiac Surgery: Biofilm in Infective Endocarditis. Semin Thorac Cardiovasc Surg. 2016;28:56-59. doi: 10.1053/j.semtcvs.2015.12.005

17.         Elgharably H, Ibrahim A, Rosinski B, Thuita L, Blackstone EH, Collier PH, Pettersson GB. Right heart failure and patient selection for isolated tricuspid valve surgery. The Journal of thoracic and cardiovascular surgery. 2023;166:740-751.e748. doi: 10.1016/j.jtcvs.2021.10.059

18.         Elgharably H, Javadikasgari H, Koprivanac M, Lowry AM, Sato K, Blackstone EH, Klein AL, Gillinov AM, Svensson LG, Navia JL. Right versus left heart reverse remodelling after treating ischaemic mitral and tricuspid regurgitation. Eur J Cardiothorac Surg. 2020. doi: 10.1093/ejcts/ezaa326

19.         Elgharably H, Javorski MJ, McCurry KR. Bilateral sequential lung transplantation: technical aspects. J Thorac Dis. 2021;13:6564-6575. doi: 10.21037/jtd-2021-22

20.         Elgharably H, Kursbaum A, Flamm SD, Navia JL. Mediastinal mass presented 36 years after coronary bypass grafting: is vein graft pseudoaneurysm a differential diagnosis? Eur J Cardiothorac Surg. 2015;48:166-168. doi: 10.1093/ejcts/ezu342

21.         Elgharably H, Mann E, Awad H, Ganesh K, Ghatak PD, Gordillo G, Sai-Sudhakar CB, Roy S, Wozniak DJ, Sen CK. First evidence of sternal wound biofilm following cardiac surgery. PLoS One. 2013;8:e70360. doi: 10.1371/journal.pone.0070360

22.         Elgharably H, Okamoto T, Ayyat KS, Niikawa H, Meade S, Farver C, Chan ER, Aldred MA, McCurry KR. Human Lungs Airway Epithelium Upregulate MicroRNA-17 and MicroRNA-548b in Response to Cold Ischemia and Ex Vivo Reperfusion. Transplantation. 2020;104:1842-1852. doi: 10.1097/tp.0000000000003370

23.         Elgharably H, Pettersson GB, Navia JL. Aortic Allograft for Endocarditis of the Intervalvular Fibrosa. Ann Thorac Surg. 2021;112:1383-1384. doi: 10.1016/j.athoracsur.2020.11.085

24.         Elgharably H, Roy S, Khanna S, Abas M, Dasghatak P, Das A, Mohammed K, Sen CK. A modified collagen gel enhances healing outcome in a preclinical swine model of excisional wounds. Wound Repair Regen. 2013;21:473-481. doi: 10.1111/wrr.12039

25.         Elgharably H, Shafii AE, Mason DP. Expanding the donor pool: donation after cardiac death. Thorac Surg Clin. 2015;25:35-46. doi: 10.1016/j.thorsurg.2014.09.011

26.         Elgharably H, Tong MZ, Soltesz EG. HeartMate 3 Implantation in a Myosplint Device-Supported Left Ventricle. Ann Thorac Surg. 2020;109:e177-e178. doi: 10.1016/j.athoracsur.2019.06.088

27.         Elgharably H, Unai S, Pettersson GB. Sutureless Prosthesis for Prosthetic Aortic Valve Endocarditis: Time to put Brakes on a Speedy Bus? Ann Thorac Surg. 2024. doi: 10.1016/j.athoracsur.2024.01.014

28.         Hanks J, Unai S, Bribriesco A, Insler S, Yu E, Banzon J, Mireles-Cabodevila E, Adi A, Elgharably H, Yun J, et al. Successful treatment of pulmonary mucormycosis (Lichtheimia spp.) in a post-partum patient with COVID-19 ARDS requiring extra-corporeal membrane oxygenation using salvage therapy. Perfusion. 2023;38:1315-1318. doi: 10.1177/02676591221111031

29.         Harb SC, Rodriguez LL, Svensson LG, Xu B, Elgharably H, Klatte R, Krishnaswamy A, Grimm RA, Griffin BP, Kapadia SR, et al. Pitfalls and Pearls for 3-Dimensional Printing of the Tricuspid Valve in the Procedural Planning of Percutaneous Transcatheter Therapies. JACC Cardiovasc Imaging. 2018;11:1531-1534. doi: 10.1016/j.jcmg.2018.05.003

30.         Hariri E, Layoun H, Hansen J, Abou Hassan O, Kassab J, Kassis N, Cremer PC, Hanna M, Mentias A, Flamm SD, et al. Imaging and haemodynamic parameters associated with clinical outcomes following isolated tricuspid valve surgery. Open Heart. 2022;9. doi: 10.1136/openhrt-2022-002124

31.         Insler JE, Tipton AE, Bakaeen FG, Bakhos JJ, Houghtaling PL, Blackstone EH, Roselli EE, Soltesz EG, Tong MZ, Unai S, et al. What determines outcomes in multivalve reoperations? Effect of patient and surgical complexity. The Journal of thoracic and cardiovascular surgery. 2023. doi: 10.1016/j.jtcvs.2023.12.005

32.         Javorski MJ, Rosinski BF, Shah S, Thompson MA, Streem D, Gordon SM, Insler S, Houghtaling PL, Griffin B, Blackstone EH, et al. Infective Endocarditis in Patients Addicted to Injected Opioid Drugs. J Am Coll Cardiol. 2024;83:811-823. doi: 10.1016/j.jacc.2023.12.016

33.         Javorski MJ, Xu B, Fraser T, Elgharably H. A 73-Year-Old Woman with a Fall. NEJM Evid. 2023;2:EVIDmr2300254. doi: 10.1056/EVIDmr2300254

34.         Javorski MJ, Zaki A, Abas M, Elgharably H, Attia TS. The current era of left ventricular assist devices. Future Cardiol. 2021;17:971-984. doi: 10.2217/fca-2020-0177

35.         Jenkins H, Elkilany I, Guler E, Cummins K, Ayyat K, Pennacchio C, Kapadia SR, Bakaeen F, Gillinov AM, Svensson LG, et al. Predictors and outcomes of discharge to long-term acute care facilities after cardiac surgery. The Journal of thoracic and cardiovascular surgery. 2024. doi: 10.1016/j.jtcvs.2024.01.029

36.         Johnston DR, Mahboubi R, Soltesz EG, Artis AS, Roselli EE, Blackstone EH, Svensson LG. Redefining "low risk": Outcomes of surgical aortic valve replacement in low-risk patients in the transcatheter aortic valve replacement era. The Journal of thoracic and cardiovascular surgery. 2023;165:591-604.e593. doi: 10.1016/j.jtcvs.2021.01.145

37.         Kakavand M, Stembal F, Chen L, Mahboubi R, Layoun H, Harb SC, Xiang F, Elgharably H, Soltesz EG, Bakaeen FG, et al. Contemporary experience with the Commando procedure for anterior mitral anular calcification. JTCVS Open. 2024;18:12-30. doi: 10.1016/j.xjon.2023.10.038

38.         Kassab J, Harb SC, Desai MY, Gillinov AM, Layoun H, El Dahdah J, Chedid El Helou M, Nakhla S, Elgharably H, Kapadia SR, et al. Incidence, Risk Factors, and Outcomes Associated With Permanent Pacemaker Implantation Following Tricuspid Valve Surgery. J Am Heart Assoc. 2024;13:e032760. doi: 10.1161/jaha.123.032760

39.         Kelava M, Milam AJ, Mi J, Alfirevic A, Grady P, Unai S, Elgharably H, McCurry K, Koprivanac M, Duncan A. Arterial Hyperoxemia During Cardiopulmonary Bypass Was Not Associated With Worse Postoperative Pulmonary Function: A Retrospective Cohort Study. Anesth Analg. 2024;138:1003-1010. doi: 10.1213/ane.0000000000006627

40.         Krishnan S, Soltesz E, Hanks J, Adi A, Elgharably H, McCurry K, Bribriesco A. Radiation Exposure in Extracorporeal Life Support. Asaio j. 2023;69:1049-1054. doi: 10.1097/mat.0000000000002037

41.         Mansfield SA, Dwivedi V, Elgharably H, Griessl M, Zimmerman PD, Limaye AP, Cook CH. Cytomegalovirus immunoglobulin G titers do not predict reactivation risk in immunocompetent hosts. J Med Virol. 2019;91:836-844. doi: 10.1002/jmv.25389

42.         Navia JL, Baeza C, Maluenda G, Kapadia S, Elgharably H, Sadowski J, Bartuś K, Beghi C, Thyagarajan K, Bertwell R, et al. Transcatheter mitral valve replacement with the NaviGate stent in a preclinical model. EuroIntervention. 2017;13:e1401-e1409. doi: 10.4244/eij-d-17-00210

43.         Navia JL, Elgharably H, Hakim AH, Witten JC, Haupt MJ, Germano E, Houghtaling PL, Bakaeen FG, Pettersson GB, Lytle BW, et al. Long-term Outcomes of Surgery for Invasive Valvular Endocarditis Involving the Aortomitral Fibrosa. Ann Thorac Surg. 2019;108:1314-1323. doi: 10.1016/j.athoracsur.2019.04.119

44.         Navia JL, Elgharably H, Javadikasgari H, Ibrahim A, Koprivanac M, Lowry AM, Blackstone EH, Klein AL, Gillinov AM, Roselli EE, et al. Tricuspid Regurgitation Associated With Ischemic Mitral Regurgitation: Characterization, Evolution After Mitral Surgery, and Value of Tricuspid Repair. Ann Thorac Surg. 2017;104:501-509. doi: 10.1016/j.athoracsur.2016.11.024

45.         Navia JL, Kapadia S, Elgharably H, Harb SC, Krishnaswamy A, Unai S, Mick S, Rodriguez L, Hammer D, Gillinov AM, et al. First-in-Human Implantations of the NaviGate Bioprosthesis in a Severely Dilated Tricuspid Annulus and in a Failed Tricuspid Annuloplasty Ring. Circ Cardiovasc Interv. 2017;10. doi: 10.1161/circinterventions.117.005840

46.         Navia JL, Kapadia S, Elgharably H, Maluenda G, Bartuś K, Baeza C, Nair RK, Rodés-Cabau J, Beghi C, Quijano RC. Transcatheter Tricuspid Valve Implantation of NaviGate Bioprosthesis in a Preclinical Model. JACC Basic Transl Sci. 2018;3:67-79. doi: 10.1016/j.jacbts.2017.08.003

47.         Okamoto T, Ayyat KS, Sakanoue I, Niikawa H, Said SA, Ahmad U, Unai S, Bribriesco A, Elgharably H, Budev MM, et al. Clinical significance of donor lung weight at procurement and during ex vivo lung perfusion. J Heart Lung Transplant. 2022;41:818-828. doi: 10.1016/j.healun.2022.02.011

48.         Othman AA, Elgharably H, Vargo PR, Ayyat KS, Bakaeen FG, Johnston DR, Tong MZ, Unai S, Kalahasti V, Svensson LG, et al. Valve-Preserving Root Reimplantation Combined with Arch Procedure: Optimizing Patient Selection. Innovations (Phila). 2022;17:201-208. doi: 10.1177/15569845221094007

49.         Rappaport JM, Siddiqui HU, Thuita L, Budev M, McCurry KR, Blackstone EH, Ahmad U. Effect of donor smoking and substance use on post-lung transplant outcomes. The Journal of thoracic and cardiovascular surgery. 2023;166:383-393.e313. doi: 10.1016/j.jtcvs.2023.01.028

50.         Rappaport JMP, Raja S, Gabbard S, Thuita L, Sanaka MR, Blackstone EH, Ahmad U. Endoscopic pyloromyotomy is feasible and effective in improving post-lung transplant gastroparesis. The Journal of thoracic and cardiovascular surgery. 2022;164:711-719.e714. doi: 10.1016/j.jtcvs.2021.10.063

51.         Reyaldeen R, Lo Presti Vega S, Elgharably H, Xu B. More Than a Simple Vegetation: The Trifecta of Mitral Valve Leaflet Perforation, Windsock Aneurysm, and Mitral Valve Abscess. CASE (Phila). 2021;5:20-25. doi: 10.1016/j.case.2020.10.008

52.         Roselli EE, Vargo PR, Bakaeen F, Koprivanac M, Burns D, Kuramochi Y, Gillinov M. Branched stented anastomosis frozen elephant trunk repair: Early results from a physician-sponsored investigational device exemption study. The Journal of thoracic and cardiovascular surgery. 2023. doi: 10.1016/j.jtcvs.2023.09.069

53.         Roy S, Driggs J, Elgharably H, Biswas S, Findley M, Khanna S, Gnyawali U, Bergdall VK, Sen CK. Platelet-rich fibrin matrix improves wound angiogenesis via inducing endothelial cell proliferation. Wound Repair Regen. 2011;19:753-766. doi: 10.1111/j.1524-475X.2011.00740.x

54.         Roy S, Elgharably H, Sinha M, Ganesh K, Chaney S, Mann E, Miller C, Khanna S, Bergdall VK, Powell HM, et al. Mixed-species biofilm compromises wound healing by disrupting epidermal barrier function. J Pathol. 2014;233:331-343. doi: 10.1002/path.4360

55.         Schraufnagel DP, Elgharably H, Siddiqi S, Hakim AH, Sale S, Mehta A, Skubas NJ, Gordon SM, Bakaeen F, Gillinov AM, et al. Value of perioperative inhaled epoprostenol with low tidal volume ventilation for complex endocarditis surgery. J Card Surg. 2019;34:676-683. doi: 10.1111/jocs.14095

56.         Schraufnagel DP, Steffen RJ, Vargo PR, Attia T, Elgharably H, Hasan SM, Bribriesco A, Wierup P. Devices for ex vivo heart and lung perfusion. Expert Rev Med Devices. 2018;15:183-191. doi: 10.1080/17434440.2018.1430568

57.         Shah A, Elgharably H, Mehta A, Lum J. First Case of Cupravidus paculus Infection in a Lung Transplant Recipient: A Case Report. Transplant Proc. 2023;55:1984-1987. doi: 10.1016/j.transproceed.2023.05.027

58.         Siddiqi S, Ravichandren K, Soltesz EG, Johnston DR, Roselli EE, Tong MZ, Navia JL, Elgharably H, Ayyat K, Houghtaling PL, et al. Coronary Artery Bypass Graft Patency and Survival in Patients on Dialysis. J Surg Res. 2020;254:1-6. doi: 10.1016/j.jss.2020.03.069

59.         Siddiqi S, Schraufnagel DP, Siddiqui HU, Javorski MJ, Mace A, Elnaggar AS, Elgharably H, Vargo PR, Steffen R, Hasan SM, et al. Recent advancements in the minimally invasive management of esophageal perforation, leaks, and fistulae. Expert Rev Med Devices. 2019;16:197-209. doi: 10.1080/17434440.2019.1582329

60.         Umana Pizano JB, Arain FD, Harb SC, Bakaeen FG, Elgharably H. Is right ventricular free wall revascularization underrated? Sequential bypass of mid-right coronary artery to resolve acute right ventricular dysfunction. JTCVS Tech. 2023;21:118-121. doi: 10.1016/j.xjtc.2023.07.012

61.         Unai S, Khullar V, Elgharably H, Navia JL. ECMO as a Bridge to Reoperative Cardiac Surgery in a Patient with Cardiogenic Shock and Severe Aortic Insufficiency Due to an Acute Aortic Valve Homograft Failure. Heart Surg Forum. 2019;22:E281-e282. doi: 10.1532/hsf.1758

62.         Wang TKM, Elgharably H, Cremer P. "Holes-in-one": A case of concurrent windsock mitral valve, root abscess, and Gerbode defect. Echocardiography. 2020;37:935-938. doi: 10.1111/echo.14703

63.         Weingarten N, Schraufnagel D, Plitt G, Zaki A, Ayyat KS, Elgharably H. Comparison of mechanical cardiopulmonary support strategies during lung transplantation. Expert Rev Med Devices. 2020;17:1075-1093. doi: 10.1080/17434440.2020.1841630

64.         Xu RX, Allen DW, Huang J, Gnyawali S, Melvin J, Elgharably H, Gordillo G, Huang K, Bergdall V, Litorja M, et al. Developing digital tissue phantoms for hyperspectral imaging of ischemic wounds. Biomed Opt Express. 2012;3:1433-1445. doi: 10.1364/boe.3.001433

65.         Zaki A, Witten JC, Pettersson GB, Elgharably H. Patch reconstruction of the aorto-mitral curtain without posterior extension: Alternative to the Commando procedure for double valve replacement. JTCVS Tech. 2023;22:181-184. doi: 10.1016/j.xjtc.2023.08.021