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Effect of Thoracoscopic Talc Poudrage Versus Talc Slurry via Chest Tube on Pleurodesis Failure Rate Among Patients With Malignant Pleural Effusions

Wednesday, January 8, 2020

Submitted by

Mark Ferguson

Source

Source Name: JAMA

Source URL: https://jamanetwork.com/journals/jama/fullarticle/2757281?guestAccessKey=00f8e37…

Author(s)

Rahul Bhatnagar, Hania E. G. Piotrowska, Magda Laskawiec-Szkonter, Brennan C. Kahan, Ramon Luengo-Fernandez, Justin C. T. Pepperell, Matthew D. Evison, Jayne Holme, Mohamed Al-Aloul, Ioannis Psallidas, Wei Shen Lim, Kevin G. Blyth, Mark E. Roberts, Giles Cox, Nicola J. Downer, Jurgen Herre, Pasupathy Sivasothy, Daniel Menzies, Mohammed Munavvar, Moe M. Kyi, Liju Ahmed, Alex G. West, Richard N. Harrison, Benjamin Prudon, Gihan Hettiarachchi, Biswajit Chakrabarti, Ajikumar Kavidasan, Benjamin P. Sutton, Natalie J. Zahan-Evans, Jack L. Quaddy, Anthony J. Edey, Amelia O. Clive, Steven P. Walker, Matthew H. R. Little, Xue W. Mei, John E. Harvey, Clare E. Hooper, Helen E. Davies, Mark Slade, Merle Sivier, Robert F. Miller, Najib M. Rahman, Nick A. Maskell

In this randomized trial including 330 pts with MPE, talc slurry and VATS talc insufflation under local anesthesia had similar failure rates (24% vs 22%) at 90 days.