This randomized trial evaluating the relative efficacy of immunotherapy and chemotherapy in patients with recurrent or metastatic disease, immunotherapy was associated with significantly better progression-free survival. Tumor mutational burden was a marker for patient selection for immunotherapy.
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Lung - Cancer
May 30, 2018
The addition of pembrolizumab (targeting PD-1) to standard chemotherapy substantially improved time to progression and overall survival compared to chemotherapy alone in patients with metastatic lung cancer.
May 25, 2018
Find it here: The 26th ESTS Meeting in Ljubljana, Slovenia.
May 23, 2018
The age-specific incidence of non-small cell lung cancer has reversed in individuals born since the 1960s, with women now having a higher incidence than men. This trend is not explained by differences in smoking habits.
May 23, 2018
This is among the first and largest summaries of the use of neoadjuvant PD-1 inhibitor (nivolumab) in patients with resectable lung cancer. The safety profile was adequate, 20 of 21 patients underwent complete resection, and the pathologic major response rate was 45%. The response was similar regardless of PD-L1 status, and response was related to
May 23, 2018
The author demonstrates a uniportal fissureless approach to resect the anterior segment of the right upper lobe, followed by lymph node dissection.
May 23, 2018
Using eight computed tomography radiographic features in an automated algorithm, differentiating between benign and malignant status of indeterminate pulmonary nodules had an area under the curve of 0.939.
May 19, 2018
This overview of some recent social science flavored research identifies challenges associated with stigma attached to a lung cancer diagnosis. These challenges include decreased participation in screening tests, noncompliance with therapy, and poor communication with treating physicians.
May 18, 2018
Patient Care
Three-dimensional heart models help patients and families understand congenital heart defects at a hospital in Seattle, Washington, USA.
May 14, 2018
The authors demonstrate a hybrid uniportal VATS left upper lobectomy with chest wall resection and reconstruction.