An overview of the basic pharmacology of commonly used cardiovascularly active drugs.
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Vascular
March 24, 2016
For you chocolate lovers out there, hard evidence that dark chocolate can boost endurance performance.
March 18, 2016
Not only an authoritative 16 year retrospective report on 957 planned aortic aneurysm surgeries from Cleveland Clinic, but a stimulating critique ( pages 771-774) with Tyrone David who was the invited discussant of the manuscript at its presentation at the AATS last April.
March 4, 2016
Surgical intervention in older people is increasing in prevalance but is associated with higher rates of adverse postoperative outcomes as compared to younger people. Current models of preoperative risk assessment and optimisation may be indequate for this complex surgical population.
February 18, 2016
An Editorial suggesting that atheroma is here to stay...
February 18, 2016
The authors studied the rate of publication of completed clinical trials performed in academic medical centers in the US. Among over 4,300 such trials, only 36% were published within 2 years of completion, and only 66% were ultimately published at any time. There was considerable variation in publication rates among institutions.
February 18, 2016
The authors studied the relationship of outcomes after non-cardiac surgery to blood transfusion among over 7,300 patients. Patients with significant bleeding were excluded. Patients were stratified according to the occurence of postoperative MI and the nadir hematocrit value (20-24%, 24-27%, 27-30%). The outcome was 30-day mortality. In the no-
February 18, 2016
The authors studied outcomes after endovascular AAA aneurysm repair (EVAR) to assess whether ongoing aortic remodeling related to systemic inflammatory disease (SID) contributes to an increased incidence of endoleak. 65% of 79 treated patients had systemic inflammatory disease. Major complication rates were increased 7-fold in the group with SID.
February 18, 2016
Over 1400 patients with asymptomatic severe carotid stenosis were randomized to with carotid stenting or endarterectomy. The endpoints were the composite of death, stroke, or acute MI within 30 days, or ipsilateral stroke. Stenting was non-inferior to endarterectomy. The rate of the composite endpoint was 3.8% vs 3.4% (stent vs surgery). At 30
February 5, 2016
A useful reference tool for all colleagues interested in research and biomedical publishing