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Aspirin in Patients Undergoing Noncardiac Surgery

Tuesday, April 1, 2014

Submitted by

Mark Ferguson

Source

Source Name: New England Journal of Medicine

Source URL: http://www.nejm.org/doi/full/10.1056/NEJMoa1401105?query=OF

Author(s)

PJ Devereaux and other for the POISE-2 Investigators

This randomized trial including more than 10,000 patients undergoing noncardiac surgery evaluated the use of perioperative aspirin in patients at increased risk for vascular complications. The end points were death or MI. The end points occurred in equal numbers (7%) in both groups. Bleeding complications were more common in the aspirin group (4.6% vs 3.8%).