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Assessing Donor-Recipient Size Mismatch in Pediatric Heart Transplantation: Lessons Learned from Over 7,500 Transplants

Thursday, October 26, 2023

Submitted by

Malak Elbatarny

Source

Source Name: JACC

Source URL: https://www.jacc.org/doi/10.1016/j.jchf.2023.07.005

Author(s)

Shahnawaz Amdani, Othman A. Aljohani, James K. Kirklin, Ryan Cantor, Devin Koehl, Kurt Schumacher, Deipanjan Nandi, Michael Khoury, William Dreyer, Kirsten Rose-Felker, Colleen Nasman, and Mariska S. Kemna

This study determined which measurement—height, weight, BMI, BSA, predicted heart mass, total cardiac volume (TCV)—is most important for assessing donor-recipient heart size mismatch. Amdani and colleagues investigated the Pediatric Heart Transplant Society Database to address this question and identify the effects of donor-recipient size mismatch using a range of parameters. Outcomes were assessed at one and five years of follow up. Interestingly, they report that height and TCV are more relevant to long-term risk of graft loss compared to other metrics.