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Effect of Screening for Coronary Artery Disease Using CT Angiography on Mortality and Cardiac Events in High-Risk Patients With Diabetes - the FACTOR-64 Randomized Clinical Trial

Monday, November 17, 2014

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Author(s)

Joseph B. Muhlestein; Donald L. Lappé; Joao A. C. Lima; Boaz D. Rosen; Heidi T. May; Stacey Knight; David A. Bluemke; Steven R. Towner; Viet Le; Tami L. Bair; Andrea L. Vavere; Jeffrey L. Anderson

This trial randomized 900 pts with type 1 or 2 diabetes to screening with coronary computed tomography angiography (CCTA) or standard care and evaluated death and non-fatal coronary outcomes.  The major outcome was a composite of death, MI, and admission for management of unstable angina.  The secondary outcome was a composite of CAD-associated death, MI, or unstable angina.  CCTA screening did not influence the rate of major or secondary outcomes.

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