ALERT!

This site is not optimized for Internet Explorer 8 (or older).

Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.

Is Epinephrine During Cardiac Arrest Associated With Worse Outcomes in Resuscitated Patients?

Wednesday, December 3, 2014

Submitted by

Mark Ferguson

Source

Source Name: Journal of the American College of Cardiology

Source URL: http://content.onlinejacc.org/article.aspx?articleID=2020181

Author(s)

Florence Dumas; Wulfran Bougouin; Guillaume Geri; Lionel Lamhaut; Adrien Bougle; Fabrice Daviaud; Tristan Morichau-Beauchant; Julien Rosencher; Eloi Marijon; Pierre Carli; Xavier Jouven; Thomas D. Rea; Alain Cariou

This study determined the relationship of pre-hospital use of epinephrine during resuscitation to survival in patients who experienced return of spontaneous circulation after out of hospital cardiac arrest. 73% received epinephrine, and 17% of those patients experienced a good outcome (discharged alive with good neurologic status). Of those who did not received epinephrine, 63% had a good outcome. There was a dose-response effect. Delayed administration of epinephrine had the worst outcomes.