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Remote Ischemic Post-Conditioning of the Lower Limb During Primary Percutaneous Coronary Intervention Safely Reduces Enzymatic Infarct Size in Anterior Myocardial Infarction:

Wednesday, October 23, 2013

Submitted by

Source

Source Name: JACC Cardiovascular Interventions

Source URL: http://interventions.onlinejacc.org/article.aspx?articleid=1758471

Author(s)

Gabriele Crimi; Silvia Pica; Claudia Raineri; Ezio Bramucci; Gaetano M. De Ferrari; Catherine Klersy; Marco Ferlini; Barbara Marinoni; Alessandra Repetto; Maurizio Romeo; Vittorio Rosti; Margherita Massa; Arturo Raisaro; Sergio Leonardi; Paolo Rubartelli; Luigi Oltrona Visconti; Maurizio Ferrario

In this randomized trial involving 100 pts requiring PCI for STEMI and occluded LAD, half received lower extremity preconditioning for 3 cycles of 5min/5min ischemia/reperfusion. Preconditioning reduced enzymatic infarct size, reduced myocardial edema, and provided greater improvement in ST segment resolution.