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Targeted Temperature Management at 33°C versus 36°C after Cardiac Arrest

Monday, November 18, 2013

Submitted by

Source

Source Name: New England Journal of Medicine

Source URL: http://www.nejm.org/doi/full/10.1056/NEJMoa1310519?query=featured_home

Author(s)

N Nielsen and others for the TTM Trial Investigators

Hypothermia is recommended for unconscious survivors of out-of-hospital cardiac arrest to preserve heart and neurologic function. This study randomized 950 pts to determine whether 33º C or 36º C is the most appropriate target temperature. Mortality was similar (50% vs 48%) and outcomes at 180 days for mortality and poor neurologic function were also similar (54% vs 52%).