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The Unnatural History of Tetralogy of Fallot: Prospective Follow-Up of 40 Years After Surgical Correction.

Thursday, November 13, 2014

Submitted by

Ruben Osnabrugge

Source

Source Name: Circulation

Source URL: http://www.ncbi.nlm.nih.gov/pubmed/25341442

Author(s)

Cuypers JA, Menting ME, Konings EE , Opić P, Utens EM, Helbing WA, Witsenburg M, van den Bosch AE, Ouhlous M, van Domburg RT, Rizopoulos D, Meijboom FJ, Boersma E, Bogers AJ, Roos-Hesselink JW

The authors of this article aimed to describe survival and clinical outcomes beyond 30 years of follow-up after surgical repair of Tetralogy of Fallot. They found a survival of 72% after 40 years. Health status was comparable to the Dutch population. Factors that were associated with late mortality included: a prior shunt operation, low temperature during surgery and early postoperative arrhythmias. They conclude that although many patients needed reoperation or developed arrhythmias, long-term survival was good, as was health status.