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Cardiac - Physiology

November 6, 2023
An elegant and surprisingly easily read cohort study of mechanical destruction of platelets in ECMO circuits that parallels what we already know in pumps for full cardiopulmonary bypass. The authors propose a biomarker as a target for thrombotic modulation .
August 7, 2023
In a research letter on a small pilot genomic study of sampling coronary atheroma, the authors offer a brief explanation on how their technique can be applied to detect stability of coronary plaque.
September 30, 2022
This editorial describes the evolving pathway of diagnosing a disease that is predicted to augment the indication for orthotopic cardiac transplantation. Cardiac involvement of sarcoidosis accounts for the majority of deaths in sarcoidosis patients, so it is important to better understand its symptoms.
September 20, 2022
Plasma metabolomic profiles were examined to determine differences in social determinants of health between Black and white women. This observational study paves the groundwork for further investigation of social disparity in atheromatous disease.
April 19, 2022
Interesting manuscript on the immunology of coronary atheroma, with tanslational potential in therapies and prevention of ischaemic heart disease.
April 5, 2022
A brief but comprehensive editorial on nuances of the links between atrial fibrillation and heart failure, apropos a trial we have commented recently on, by the Johns Hopkins team that develops the calmodulin-dependent protein kinase II inhibitor molecules   
March 4, 2022
A paper that addresses a gap in knowledge and will guide future research: of particular interest, the penultimate paragraph on The Role of Interventions.
February 28, 2022
An interesting brief editorial on an experiment revisiting renal denervation as a panacea to cardiovascular disease
February 24, 2022
Interesting study of hypertrophied human cardiomyocytes
January 21, 2022
An editorial  with some interest for the cardiothoracic surgeon, in particular the awareness of changes in the right vantricle during ECMO support , mostly drawn from the recent Covid experiences, and with a useful paragraph on veno-pulmonary arterial ECMO, discussing the uncoupling of RV and PA. 

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