This murine model study investigated a novel combination treatment for pleural mesothelioma using intracavitary cisplatin-fibrin gel (cis-fib) and adjuvant irradiation (IR). Conducted on an orthotopic immunocompetent rat model, the study demonstrates that the combination therapy significantly delayed tumor growth compared to single treatments.
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Lung - Cancer
January 30, 2025
January 2, 2025
This study evaluates the outcomes of bilateral lung transplantation (LTx) using grafts from donors aged 70 years or older, compared with those from younger donors. Conducted at a single center in Leuven, Belgium, the retrospective cohort study included 69 older donors, matched 1:1 with younger donors based on key variables.
Prevalence of Invasive Lung Cancer in Pure Ground Glass Nodules Less Than 30 mm: A Systematic Review
December 19, 2024
This article examines the malignancy potential of pure ground-glass nodules (pGGNs) under 30 mm, challenging the notion that these nodules carry minimal invasive cancer risk.
December 5, 2024
This article provides a consensus-based approach for determining the resectability and optimal management strategies for locally advanced non-small cell lung cancer (NSCLC).
December 5, 2024
This article assesses the outcomes of segmentectomy versus lobectomy in treating peripheral, early-stage lung adenocarcinoma. In a multicenter study involving 674 patients, the authors compared overall survival (OS), lung cancer-specific survival (LCSS), and disease-free survival (DFS) between the two groups.
November 7, 2024
Recently, the CALGB 140503 trial and the JCOG0802/WJOG4607L showed the non-inferiority of sublobar resections compared to lobectomy for <2cm non-small cell lung cancer.
November 7, 2024
This article explores the disparities in access to minimally invasive surgery (MIS) for stage I non-small cell lung cancer (NSCLC) based on socioeconomic status.
October 24, 2024
This article evaluates the effectiveness of neoadjuvant immunotherapy combined with chemotherapy (IC+Chemo) in treating non-small cell lung cancer (NSCLC). This large-scale study involved 1,092 patients from 11 medical centers and compared outcomes between those who received IC+Chemo and those who received chemotherapy alone.
October 10, 2024
CT-guided transthoracic needle biopsy (TNB) has allowed for increased detection of small pulmonary nodules in lung cancer patients. However, it also poses a risk of iatrogenic damage. This single-center study aimed to investigate the risk profile of preoperative CT-guided TNB.
October 3, 2024
This article examines how different follow-up frequencies affect outcomes in patients with lung cancer post-resection. The study analyzed 1,916 patients and compared low-frequency (LF) and high-frequency (HF) radiological surveillance.