An interesting, informative, and timely consensus statement on mitochondrial dysfunction in heart failure and how to potentially target these abnormalities therapeutically.
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Physiology
May 22, 2018
May 3, 2018
The latest on portable venovenous ECMO in a cohort in which half of the subjects died after a resource-intensive treatment. The results of the relevant EOLIA trial are keenly awaited.
March 21, 2018
One of the more contentious issues in Enhanced Recovery After Surgery (ERAS) programs is the role of preoperative carbohydrate loading. This randomized trial demonstrated less need for insulin for treating serum glucose >180 mg/dl in the carbohydrate-loading group compared to the placebo group (2.4% versus 16.0%; RR 0.15; p<0.001) with no chan
October 18, 2017
The authors report the non-intuitive finding that blood from female donors who had ever been pregnant was associated with increased mortality among male recipients (HR 1.13). If validated by other studies, might this substantially complicate matching donated blood with appropriate recipients? Clearly the underlying mechanism will be interesting to
September 25, 2017
The authors conducted a double-blinded prospective, randomized clinical trial in 249 patients >60 years of age who underwent cardiac surgery with cardiopulmonary bypass to assess whether interventions based on cerebral oximetry would decrease the incidence of postoperative delirium. Two groups were compared: The control group, in which the resul
June 13, 2017
A succinct review of cardiac amyloidosis, particularly relevant to transplant surgeons that are expected to see more patients with the condition
August 8, 2016
A bona fide new technique applied in a handful of low-risk deep sternal wound infections. It will be interesting to see the follow-up and perhaps some cardiothoracic surgical input to the efforts of the esteemed plastic surgical colleague who is the sole author.
July 5, 2016
Acute kidney injury (AKI) complicates recovery from cardiac surgery in up to 30% of patients, injures and impairs the function of the brain, lungs, and gut, and places patients at a 5-fold increased risk of death during hospitalization.
May 8, 2016
The entire issue is dedicated to thrombosis and makes a compulsory read for cardiovascular and thoracic hospitalists. Of patricular relevance to the thoracic surgeon are the translational articles on system analysis (page 1348) and the table on oral anticoagulants on page 1410.
May 8, 2016
A collaborative multi-funded RCT by Chinese surgeons and European epidemiologists, this article is guaranteed to elicit thunderous responses from biomedical publishing and the pharmaceutical industry.