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Heart Failure

March 27, 2025
The authors aimed to explore the applicability of the benefits of early mobility and ambulation for patients receiving extracorporeal membrane oxygenation (ECMO).
February 27, 2025
This article presents findings from the second-ever pig-to-human heart xenotransplant. A 58-year-old patient with end-stage heart failure received a 10-gene-edited porcine heart and was maintained on a novel anti-CD40L immunosuppressive regimen.
February 13, 2025
Researchers have shown that patches of muscle grown from stem cells can help repair a failing heart. A laboratory-grown biological transplant with the potential to stabilize and strengthen the heart muscle can be implanted onto the heart surface.
February 13, 2025
Proper preservation of the myocardium during intraoperative ischemia is a critical predictor of satisfactory clinical outcomes. However, there can be a wide degree of diversity in myocardial damage among patients receiving the same cardioplegic solution.
January 16, 2025
In this study-level meta-analysis of randomized controlled trials (RCTs) evaluating the effect of early aortic valve replacement (AVR) versus clinical surveillance (CS) in patients with asymptomatic severe aortic stenosis (AS), four RCTs were identified and included for analysis: AVATAR, RECOVERY, EARLY TAVR, EVOLVED.
November 26, 2024
Neurohormonal modulation and afterload reduction are essential for treating heart failure with reduced ejection fraction (HFrEF). In HFrEF patients with concomitant moderate aortic stenosis (AS), therapy with transcatheter aortic valve replacement (TAVR) may be complementary to guideline-directed medical therapy (GDMT).
November 26, 2024
In this article, the authors detail the seven pillars for successful management of tricuspid valve endocarditis. Surgical indications for tricuspid valve endocarditis include heart failure, uncontrolled infection, and septic emboli risk.
May 18, 2024
Succinct but comprehensive expert viewpoint on Support in Cardiogenic Shock vis -a -vis the manuscript of DanGer trial on promising results of Impella in highly selected subgroup (360 patients in a decade). The important point made is that of careful selection
May 2, 2024
Aortic valve regurgitation (AR) often occurs after left ventricular assist device (LVAD) implantation. Transcatheter aortic valve implantation (TAVI) is a viable alternative to surgical aortic valve replacement (SAVR) in this cohort, most of whom have a high surgical risk profile. Procedure outcome and survival were analyzed.
May 2, 2024
A fifty-four-year-old woman became the first person to simultaneously receive a gene-edited pig kidney transplant and mechanical heart valve implantation. Surgeons performed the heart pump procedure first before performing the transplant days later.

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