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Esophagus

June 22, 2014
This prospective study evaluated the relationship of inflammatory gene polymorphisms and postoperative pneumonia after esophagectomy in 120 pts.  One genotype for IL-10 was significantly associated with reduced postoperative serum IL-10 levels and an increased rate of postoperative pneumonia.  IL-10 polymorphism was an independent predictor of pneumo
June 12, 2014
Francis Nichols of the Mayo Clinic discusses use and implantation techniques of a LINX device to manage gastro-esophageal reflux disease (GERD).
June 10, 2014
Dawn Jaroszewski, Assistant Professor at the Mayo Clinic (Arizona), discusses the potential advantages of minimally invasive esophagectomy (MIE) over open esophagectomy, and shares the Mayo Clinic’s current method for MIE.
June 5, 2014
This article describes a simplified Collis gastroplasty technique performed via left chest, which negates the need for wedge fundectomy. This technique potentially saves OR time and cost, while hypothetically reducing morbidity.
May 29, 2014
This retrospective review included 322 pts undergoing open esophagectomy 2005-2010.  Gastric empyting procedures included Botox (78), pyloroplasty (199), and pyloromyotomy (45).  Botox was associated with more postop reflux symptoms and required more prokinetic agents.
May 28, 2014
  Extracapsular spread of cancer cells is associated with poorer outcome compared to intracapsular limitation in positive lymphnodes in patients with adenocarcinoma of the oesophagus and gastro-oesophageal junction. This finding is not reflected by the current tumour staging system.  
May 27, 2014
This metanalysis identified 26 eligible studies that assess the predictive value of PET for survival after induction therapy.  Complete metabolic response was associated with a 50% decrease in mortality and in tumor recurrence compared to no response.   
May 27, 2014
This retrospective single institution review assessed the incidence of hiatal hernia after minimally invasive esophagectomy (MIE).  Of 114 patients followed, 9 (8%) developed herniation, of whom 5 were symptomatic.  All were repaired laparoscopically, except 2 who underwent emergent surgery, with good results.
May 27, 2014
POEM is being increasingly used for primary treatment of achalasia.  This study evaluated POEM use for retreatment of 5 achalasia patients after prior laparoscopic esophageal myotomy and compared their results to 3 patients who underwent redo laparoscopic surgery.  Both groups had similar low complication rates and improved symptoms at intermediate-t
May 23, 2014
Stepped wedged cluster randomized control trial from the World Health Organization comparing outcomes in those who received a Checklist.  Implementation of the WHO Surgical Safey Checklist decreased morbidty and hospital length of stay.

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