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Heart failure

August 6, 2015
This retrospective analysis of the BTT continuous flow (CF) LVAD experience from Harefield Hospital addresses the question: "What are the predictors of the requirement for an RVAD at the time of LVAD implantation?" Of the 152 patients included in the study, 23% underwent RVAD implantation.
July 21, 2015
The presence of lymphoma within the heart has both local and systemic effects. This case report describes a patient who presented with evidence of right-sided heart failure secondary to cardiac involvement of systemic lymphoma.
June 30, 2015
In this video, the authors describe their experience using a percutaneous left ventricular assist device (LVAD) as a bridge to transplant in a morbidly obese pediatric patient with severe heart failure due to viral myocarditis.
May 17, 2015
The question of whether digoxin increases the risk of death in patients with atrial fibrillation (AF) or congestive heart failure (CHF) continues to be a matter of debate. The authors of this manuscript attempt to find an answer with a meta-analysis and systematic review of the literature.
May 10, 2015
This is a follow up study by the investigators on aortic valve opening during continuous flow LVAD support. Their earlier study looked at the rate of aortic insufficiency during CF LVAD support therapy comparing patients who achieved aortic valve opening during rest versus those who did not.
April 9, 2015
This concensus statement reviews the unique physiology, insertion techniques, and clinical indications for use of percutaneous mechanical circulatory support devices.  As the options for management of different etiologies of heart failure in adult and pediatric populations expand, understanding the advantages of specific devices is vital. 
March 2, 2015
This interesting article mapped myocardial remodeling in swine after induced MI using serial 3D MRI imaging.  Principal strain magnitude and angle were measured, and demonstrated progressive decrease in magnitude and angle rotation away from the site of injury, resulting in adverse remodeling and decreased contractility. 
March 2, 2015
The authors retrospectively analyze outcomes for patients placed on ECMO for cardiogenic shock, and separately analyze the patients depending on whether the ECMO support was for isolated acute cardiogenic shock or for acute-upon-chronic cardiogenic shock.
February 25, 2015
This study describes the development and validation of a risk score for post-operative mortality in patients undergoing surgical ventricular reconstruction (SVR). The study included data on 525 patients who underwent SVR at a single institution since 2001. Most patients (93%) had cocomitant CABG and 27% of patients had concomitant mitral surgery.
January 25, 2015
This study from the University of Texas Southwestern sought to analyze the effects of mechanical unloading during prolonged LVAD support on mitochondrial mass, DNA damage response (DDR), and cardiomyocyte proliferation.  Ten matched human samples of LV myocardium were analyzed before and after mechanical circulatory support.

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