The entire issue is dedicated to thrombosis and makes a compulsory read for cardiovascular and thoracic hospitalists. Of patricular relevance to the thoracic surgeon are the translational articles on system analysis (page 1348) and the table on oral anticoagulants on page 1410.
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Vascular
February 18, 2016
An Editorial suggesting that atheroma is here to stay...
February 18, 2016
Over 1400 patients with asymptomatic severe carotid stenosis were randomized to with carotid stenting or endarterectomy. The endpoints were the composite of death, stroke, or acute MI within 30 days, or ipsilateral stroke. Stenting was non-inferior to endarterectomy. The rate of the composite endpoint was 3.8% vs 3.4% (stent vs surgery). At 30
June 16, 2015
The good news continues regarding chocolate consumption! A study involving nearly 21,000 individuals with a median follow-up of nearly 12 years correlated cardiovascular disease with quintiles of chocolate consumption. The lowest quintile was associated with a 50% higher risk of coronary heart disease and a similar increase in stroke incidence.
January 21, 2015
This video demonstrates a technique for aortic arch debranching and reconstruction in an elderly patient.
January 14, 2015
This RCT compared daily 200mg or 300mg of FXI-ASO (an antisense oligonucleotide that reduces levels of factor XI) to daily 40mg of enoxaparin in pts undergoing knee replacement surgery. The end point was thromboembolism. FXI-ASO significantly reduced factor XI levels in a dose-response manner. FXI-ASO 200 mg was equivalent to enoxaparin in frequen
January 14, 2015
This multicenter study analyzes the utility of a "Top Gun" competition in promoting simulator use and improving technical skills among 1st-year CT Surgery residents. A coronary anastomosis simulation module was sent to most 1st-year residents in the U.S. Fifteen residents submitted baseline and final videos for evaluation.
December 11, 2014
Provocative study that analyzes lower body perfusion in a porcine model during cardiopulmonary bypass with an actuated IABP in place to effect pulsatile perfusion. Parameters of distal perfusion including measurement of pressures and microsphere perfusion indicate that flow distal to the balloon pump may be impaired.
November 2, 2014
This paper reviews the various techniques of 3D bioprinting with special attention to generation of tubes to be used as artificial blood vessels.
August 14, 2014
This double-blind placebo-controlled trial involved 153 pts undergoing elective endovascular aortic aneurysm repair, of whom half received methylprednisolone preoperatively. The intervention reduced the systemic inflammatory response from 92% to 27%, plasma IL-6 was decreased by 90%, and CRP, body temperature, IL-8, and TNF were also reduced. MMP-9