Data from 20 observational studies including nearly 3000 pts were reviewed to assess the prevalence of pre-frailty/frailty and clinical outcomes in older cancer patients. Frailty was identified in 42% and pre-frailty in 43% of patients. Combined frailty was associated with increased all cause mortality (5-yr HR 1.57), postoperative mortality, and p
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Thoracic
November 20, 2014
November 18, 2014
This video demonstrates a uniportal non-intubated VATS lobectomy in an elderly patient with a lower left lobe tumor.
November 16, 2014
This expert technique offers a step-by-step approach to right upper lobectomies through a full thoracoscopic posterior approach.
November 16, 2014
This retrospective study evaluated results of transthoracic (TTE) vs transhiatal (THE) esophagectomy in patients with squamous cell cancer and adenocarcinoma from two high volume centers.
November 16, 2014
This article systematically reviewed the impact of surgical adverse events (SAEs) on quality of life after major GI surgery. The mean difference in QOL between pts with and without SAEs was highest for esophagectomy (0.14; scale 0 to 1), while results for antireflux surgery were mixed.
November 12, 2014
This study was conducted in 94 lung adenocarcinoma patients matching pairs from current, former and never smokers' lung adenocarcinoma and non-malignant lung parenchymal tissue. Investigators discovered different smoking-specific microRNA differences.
November 11, 2014
CMS determined that the evidence of benefit for CT screening for lung cancer is sufficient to permit this as an annual benefit for Medicare and Medicaid recipients in the US. The availability of such coverage will be limited, however, by the need to have the screening as part of a comprehensive counseling (smoking cessation, etc) visit with qualifie
November 11, 2014
This study explored financial conflicts of interest (FCOI) among authors of published guidelines and consensus statements and their relationship to endorsement of specific drugs. 93% of recent articles reported FCOI status. Of articles publishing funding sources, 65% reported partial or full industry funding. Endorsement of chemotherapeutic agents
November 11, 2014
Differentiating a primary lung cancer from an intrapulmonary metastasis can be challenging. The authors developed a lineage test using whole genome amplification and next-generation sequencing to identify breakpoints in known primary tumors and known metastases. Independent primary tumors did not share any genomic rearrangements, whereas primary tu
November 10, 2014
Joel Dunning talks with Douglas Wood about key aspects of general thoracic surgery and the importance of specialization for the future of the specialty in a interview recorded at the 2014 EACTS Annual Meeting.