Gabriel Liguori graduated with honors (Highest Distinction in Surgery) in Medicine at the University of São Paulo Medical School (FMUSP), receiving the Prof. Dr. Edmundo Vasconcelos Award, in 2014. He is also one of the few scholarship holders at Fundação Estudar, an organization recognized for selecting the best students in Brazil and establishing a network of influential people both nationally and internationally.

He was the founder and first president of the Brazilian Department for Academic Leagues of Cardiovascular Surgery (DBLACCV), a body of student representation within the Brazilian Society of Cardiovascular Surgery (SBCCV). Liguori also organized and published the book "Manual Acadêmico de Cirurgia Cardiovascular" (Academic Manual of Cardiovascular Surgery), in partnership with the SBCCV and in collaboration with 113 authors from all over Brazil, making it the reference to the learning of cardiovascular surgery during graduation.

During medical school, Liguori participated in various academic activities related to cardiovascular surgery, especially pediatric cardiac surgery. He founded, in 2011, the Pediatric Cardiac Surgery League (LCCP), an academic organization dedicated to the study of congenital heart disease and its surgical treatment, becoming its first president. Liguori was also the first Junior Editor at the Brazilian Medical Association Journal (RAMB), position which he continues to occupy. He conducted observational internship at Harvard Medical School and research internships at Maastricht University and Imperial College London.

Liguori has been developing cardiovascular surgery research at the Heart Institute (InCor-HCFMUSP), acting primarily on congenital heart disease and extracorporeal circulation research lines. Currently, Liguori is studying tissue engineering at the University of Groningen in order to, someday, construct artificial organs that can address the shortage and rejection issues of the current transplants.