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A 0.6-Protamine/Heparin Ratio in Cardiac Surgery Is Associated With Decreased Transfusion of Blood Products

Friday, August 7, 2020

Submitted by

Emily Robinson

Source

Source Name: Interactive CardioVascular and Thoracic Surgery

Source URL: https://doi.org/10.1093/icvts/ivaa109

Author(s)

Anne L M Goedhart, Bastiaan M Gerritse, Thijs C D Rettig, Martijn W A van Geldorp, Sander Bramer, Nardo J M van der Meer, Leandra J Boonman-de Winter, Thierry V Scohy

Goedhart et al. investigated the effect of different heparin/protamine ratios on the amount of blood transfusions following standard cardiac surgery. In the group of patients receiving 0.6/1 protamine/heparin ratio, the fraction of patients without the need of transfusion was higher and the total blood loss was lower compared to patients treated with a 0.8/1 protamine/heparin ratio. In their patient collective, the 0.6/1 protamine/ heparin ratio proved safe and superior.