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Antithrombotic Treatment After Coronary Artery Bypass Graft Surgery: Systematic Review and Network Meta-Analysis

Friday, October 11, 2019

Submitted by

Benjamin Bidstrup

Source

Source Name: The British Medical Journal

Source URL: https://www.bmj.com/content/367/bmj.l5476?utm_source=etoc&utm_medium=email&utm_c…

Author(s)

Karla Solo, Shahar Lavi, Conrad Kabali, Glenn N Levine, Alexander Kulik, Ava A John-Baptiste, Stephen E Fremes, Janet Martin, John W Eikelboom, Marc Ruel, Ashlay A Huitema, Tawfiq Choudhury, Deepak L Bhatt, Nikolaos Tzemos, Mamas A Mamas, Rodrigo Bagur

This timely review examines the use of single and mutiple agents to decrease saphenous graft failure after CABG. These are difficult and expensive studies to perform, requiring repeat imaging after surgery, a procedure patients are often reluctant to undergo. In this analysis, the use of aspirin remains the lynchpin, with ticagrelor and clopidigrel as second agents improving outcomes, albeit at an increased in risk of bleeding.