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A Bronchial Genomic Classifier for the Diagnostic Evaluation of Lung Cancer

Tuesday, May 19, 2015

Submitted by

Mark Ferguson

Source

Source Name: New England Journal of Medicine

Source URL: http://www.nejm.org/doi/full/10.1056/NEJMoa1504601?query=featured_home

Author(s)

Gerard A. Silvestri, Anil Vachani, Duncan Whitney, Michael Elashoff, Kate Porta Smith, J. Scott Ferguson, Ed Parsons, Nandita Mitra, Jerome Brody, Marc E. Lenburg and Avrum Spira for the AEGIS Study Team

Pts with suspected lung cancer underwent sampling of normal-appearingbronchial epithelial cells in the main bronchi, unrelated to the suspected tumor. Gene expression was analyzed and classified. Classification for cancer was about 75% accurate.