Chest Wall Resection and Reconstruction for Primary Chest Wall Sarcomas: Analysis of Survival, Predictors of Outcome, and Long-Term Functional Status

This article explores the outcomes of chest wall resection and reconstruction (CWRR) in patients with primary chest wall sarcomas. Key findings of this study include an R0 resection rate of 95.5 percent, a median overall survival rate of 58.8 months and a disease-free survival rate of 53.6 months. Survival rates were significantly better in patients with chondrosarcoma compared to those with other sarcoma types. Significant predictors of mortality and recurrence were identified and included factors such as prior radiotherapy, tumor grade, and adjuvant therapy. Extended resections were also associated with higher long-term mortality, but did not significantly impact recurrence rates. 

This study highlights the importance of multidisciplinary decision-making and careful patient selection in achieving favorable outcomes in complex chest wall sarcoma cases, while also providing insights into long-term functional status and survival.