ALERT!

This site is not optimized for Internet Explorer 8 (or older).

Please upgrade to a newer version of Internet Explorer or use an alternate browser such as Chrome or Firefox.

Edoxaban versus Warfarin for the Treatment of Symptomatic Venous Thromboembolism

Thursday, October 10, 2013

Submitted by

Source

Source Name: New England Journal of Medicine

Source URL: http://www.nejm.org/doi/full/10.1056/NEJMoa1306638?query=TOC

Author(s)

The Hokusai-VTE Investigators

This randomized, double-blind study assigned pts with acute VTE who were initially treated with heparin to endoxaban or warfarin. The drugs were equivalent in preventing recurrent VTE, and endoxaban was associated with a lower risk of bleeding (p=0.004). Pts who had RV dysfunction associated with PE had a substantially reduced risk of recurrent VTE with endoxaban.