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Favorable Impact of Thoracic Endovascular Aortic Repair on Survival of Patients With Acute Uncomplicated Type B Aortic Dissection

Monday, November 26, 2018

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Source

Source Name: Journal of Vascular Surgery

Author(s)

James C. Iannuzzi, Sahael M. Stapleton, Yanik J. Bababekov, David Chang, Robert T. Lancaster, Mark F. Conrad, Richard P. Cambria, Virendra I. Patel

The authors compared the early and long-term survival in 9165 patients undergoing medical therapy (95%), open repair (2%), and thoracic endovascular aortic repair (TEVAR, 2.9%) for uncomplicated acute type B dissection. One- and 5-year survivals were 84% and 60% for medical therapy, 76% and 67% for open repair, and 85% and 76% for TEVAR (log-rank, P < .01). On risk-adjusted multivariable analysis, TEVAR had a significant survival benefit compared to medical therapy (hazard ratio, 0.68; 95% confidence interval, 0.6-0.8; P < .01).  This study on survival after acute uncomplicated type B aortic dissection shows a survival advantage for TEVAR over medical therapy. These data add further evidence for a paradigm shift in the management of acute type B dissection in favor of early TEVAR.

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