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Impact of Brain Protection Strategies on Mortality and Stroke in Patients Undergoing Aortic Arch Repair With Hypothermic Circulatory Arrest: Evidence From the Canadian Thoracic Aortic Collaborative

Friday, August 7, 2020

Submitted by

Emily Robinson

Source

Source Name: European Journal of Cardio-Thoracic Surgery

Source URL: https://doi.org/10.1093/ejcts/ezaa023

Author(s)

Ali Hage, Louis-Mathieu Stevens, Maral Ouzounian, Jennifer Chung, Ismail El-Hamamsy, Vincent Chauvette, Francois Dagenais, Andreanne Cartier, Mark D Peterson, Munir Boodhwani, Ming Guo, John Bozinovski, Michael C Moon, Abigail White, Kanwal Kumar, Carly Lodewyks, Bindu Bittira, Darrin Payne, Michael W A Chu on behalf of the Canadian Thoracic Aortic Collaborative

This manuscript by Hage et al. retrospectively looks into the outcome of more than 2500 patients undergoing aortic arch replacement within the Canadian Thoracic Aortic Collaborative registry. They analyzed risk factors for mortality and stroke. Antegrade perfusion and perfusion at temperatures higher than 24°C were independent predictors of favorable outcomes. This data should encourage aortic surgeons to execute antegrade perfusion strategies and warmer temperature regimes during circulatory arrest for arch surgery.