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Kidney Function After Off-Pump or On-Pump Coronary Artery Bypass Graft Surgery

Thursday, June 5, 2014

Submitted by

Mark Ferguson

Source

Source Name: Journal of the American Medical Association

Source URL: http://jama.jamanetwork.com/article.aspx?articleid=1877182

Author(s)

Amit X. Garg; P. J. Devereaux; Salim Yusuf; Meaghan S. Cuerden; Chirag R. Parikh; Steven G. Coca; Michael Walsh; Richard Novick; Richard J. Cook; Anil R. Jain; Xiangbin Pan; Nicolas Noiseux; Karel Vik; Noedir A. Stolf; Andrew Ritchie; Roberto R. Favaloro; Sirish Parvathaneni; Richard P. Whitlock; Yongning Ou; Mitzi Lawrence; Andre Lamy; for the CORONARY Investigators

This large-scale study evaluated kidney function postoperatively and at 1 year after either on-pump or off-pump isolated first time CABG. Nearly 3000 pts were enrolled over a 2 year period. Outcomes were a >50% increase in creatinine within 30 days of operation (AKI) and >20% loss of GFR at 1 year. Off-pump bypass was associated with a lower incidence of AKI (17.5% vs 20.8%), but the rates of loss of kidney function at 1 year were similar (17.1% vs 15.3%).