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Late Survival and Patient-Perceived Health Status of the CHSS Dextro-Transposition of the Great Arteries Cohort

Friday, July 26, 2019

Submitted by

Wei-Guo Ma

Source

Source Name: The Annals of Thoracic Surgery

Source URL: https://doi.org/10.1016/j.athoracsur.2019.05.081

Author(s)

Paul J. Devlin, Anusha Jegatheeswaran, William G. Williams, Eugene H. Blackstone, William M. DeCampli, Linda M. Lambert, Kathleen A. Mussatto, Carol J. Prospero, Igor Bondarenko, Brian W. McCrindle

Delvin and associates reported the long-term outcomes and quality of life in patients with d-TGA after repair using data from 24 centers of the Congenital Heart Surgeons’ Society (CHSS).

Among 830 neonates operated on between 1985 and 1990, 516 underwent arterial switch, 110 had Mustard operations, 175 Senning procedures, and 29 Rastelli operations. The median duration of follow-up was 24 years, extending to just over 32 years. Survival at 30 years was over 70% for all operations: 86±8% for Rastelli, 81±5% for Mustard, 80±2% for arterial switch, and 70±4% for Senning. The risk of late death was lowest in patients with arterial switch operation. Chest pain and fainting, pacemaker implantation, and unemployment were associated with reduced self-reported health status. Arterial switch patients reported higher functional health status in all domains than did atrial switch patients.