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Long-Term Survival and Center Volume for Functionally Single-Ventricle Congenital Heart Disease in England and Wales

Friday, August 11, 2023

Submitted by

Malak Elbatarny

Source

Source Name: The Journal of Thoracic and Cardiovascular Surgery

Source URL: https://doi.org/10.1016/j.jtcvs.2022.11.018

Author(s)

Kate L. Brown, MPH, MD, Qi Huang, PhD, Elena Hadjicosta, PhD, Anna N. Seale, MD, MRCP, Victor Tsang, FRCS, David Anderson, FRCS, David Barron, MD, FRCS, Hannah Bellsham-Revell, MD, Christina Pagel, PhD, Sonya Crowe, PhD, Ferran Espuny-Pujol, PhD, Rodney Franklin, MD, FRCP, Deborah Ridout, MSc

This study reported long term outcomes of over three thousand single ventricle patients in the United Kingdom, with a median of 7.6 years. The most significant predictor of long-term survival was single ventricle subtype, with the worst outcomes observed among patients with hypoplastic left heart syndrome or unbalanced AVSD. Other negative outcome predictors were low weight at time of first procedure and acquired comorbidities. Although center volume was not a major predictor of long-term outcomes in this study, it is important to note that congenital care in the UK is highly centralized; thus, no low volume centers were captured in this study.