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A Meta‐Analysis of ≥5‐Year Mortality in Randomized Controlled Trials of Off‐Pump Versus On‐Pump Coronary Artery Bypass Grafting

Tuesday, December 11, 2018

Submitted by

Claire Vernon

Source

Source Name: Journal of Cardiac Surgery

Source URL: https://doi.org/10.1111/jocs.13828

Author(s)

Hisato Takagi, Yosuke Hari, Shohei Mitta, Norikazu Kawai, Tomo Ando, ALICE (All‐Literature Investigation of Cardiovascular Evidence) Group

Takagi and colleagues performed a meta-analysis of eight randomized controlled trials comparing on-pump and off-pump coronary artery bypass grafting (CABG). They evaluated only trials with follow-up periods of five years or longer, and they pooled hazard ratios rather than odds ratios, where possible. The authors’ analysis found an increased mortality risk with off-pump CABG.