Perioperative Management of Sickle Cell Disease in Complex Congenital Cardiac Surgery: A Compilation of Two Cases

Although preoperative exchange transfusion is frequently recommended in patients with homozygous sickle cell anemia undergoing cardiopulmonary bypass, the information regarding the ideal level of sickle hemoglobin for patients undergoing the surgery is still conflicting in the literature. This study presents two cases, adding to the literature and concluding that optimization of baseline Hb and a full team approach are essential to a successful surgery.