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Perioperative Outcomes and Survival of Modified Subxiphoid Video-Assisted Thoracoscopic Surgery Thymectomy for T2-3 Thymic Malignancies: A Retrospective Comparison Study

Thursday, February 20, 2025

Submitted by

Javeria Tariq

Source

Source Name: The Journal of Thoracic and Cardiovascular Surgery

Source URL: https://www.jtcvs.org/article/S0022-5223(24)00367-2/abstract

Author(s)

Xinyu Yang, Jiahao Jiang, Yongqiang Ao, Yuansheng Zheng, Jian Gao, Hao Wang, Fei Liang, Qun Wang, Lijie Tan, Shuai Wang, Jianyong Ding

This study compared perioperative and oncological outcomes between modified subxiphoid video-assisted thoracoscopic surgery (VATS) thymectomy and median sternotomy thymectomy for locally advanced thymic malignancies. A propensity score–matched analysis of 144 patients revealed that the VATS approach resulted in shorter operative duration, less blood loss, faster recovery, and fewer complications, with no significant difference in complete resection rates. Survival analyses indicated similar recurrence-free and overall survival between the two groups. These findings suggest that modified subxiphoid VATS thymectomy is a safe and effective alternative for selected patients, although further prospective studies are needed for long-term evaluation.