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Prevention of postoperative atrial fibrillation in open heart surgery patients by preoperative supplementation of n-3 polyunsaturated fatty acids: An updated meta-analysis

Tuesday, October 1, 2013

Submitted by

Source

Source Name: Journal of Thoracic and Cardiovascular Surgery

Source URL: http://www.jtcvsonline.org/article/S0022-5223%2813%2900317-6/abstract

Author(s)

S Costanzo, V di Niro, A di Castelnuovo, F Gianfagna, M Benedetta Donati, G de Gaetano, L la Coviello

This updated meta-analysis evaluated outcomes in 2687 pts from 8 randomized clinical trials assessing the utility of polyunsaturated fatty acids in preventing postoperative atrial fibrillation after cardiac surgery. Treatment reduced the incidence of a-fib overall by 16% to 25%. In patients undergoing isolated CABG the reduction was 34% (p=0.003).