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Pro–Surfactant Protein B As a Biomarker for Lung Cancer Prediction

Tuesday, December 17, 2013

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Source

Source Name: Journal of Clinical Oncology

Source URL: http://jco.ascopubs.org/content/31/36/4536?cmpid=jco_etoc_20December2013

Author(s)

DD Sin, M Tammemagi, S Lam, MJ Barnett, X Duan, A Tam, H Auman, Z Feng, GE Goodman, S Hanash, A Taguchi

Pro–surfactant protein B (pro-SFTPB) has been previously identified as a possible blood bio-marker for NSCLC. This study assessed whether it is an independent predictory of lung cancer development. Blood levels were measured in nearly 2500 individuals in a Candadian lung cancer screening study. The adjusted OR for pro-SFTPB was 2.22 and the area under the ROC curve (predictive accuracy) was 0.74.