Repair of Aortic Regurgitation in Young Adults: Sooner Rather Than Later

The optimal timing for AVR in young adults can be hard to predict with the lack of evidence-based guidelines. One third of a total of 172 patients recruited from a single tertiary cardiac center between 2005-2019 underwent surgery before meeting guideline indications, but they were more likely to normalize their LV postoperatively. The authors found that patients with increased LV end-systolic diameters and those who underwent previous cardiac surgery were less likely to reach LV normalization post AVR. Prosthetic valve related complications occurred in 20.3 percent of patients at an average 5.6 year follow up and freedom from further aortic reinterventions was 98 percent, 96.5 percent and 85.4 percent at one, five and ten years respectively.