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Transcatheter Mitral-Valve Repair in Patients With Heart Failure

Tuesday, September 25, 2018

Submitted by

Mark Ferguson

Source

Source Name: The New England Journal of Medicine

Source URL: https://www.nejm.org/doi/full/10.1056/NEJMoa1806640

Author(s)

Gregg W. Stone, JoAnn Lindenfeld, William T. Abraham, Saibal Kar, D. Scott Lim, Jacob M. Mishell, Brian Whisenant, Paul A. Grayburn, Michael Rinaldi, Samir R. Kapadia, Vivek Rajagopal, Ian J. Sarembock, Andreas Brieke, Steven O. Marx, David J. Cohen, Neil J. Weissman, and Michael J. Mack for the COAPT Investigators

This multicenter study evaluated the efficacy of medical therapy plus transcatheter valve repair (MitraClip) to medical therapy alone for heart failure accompanied by secondary moderate to severe mitral regurgitation. The device group experienced significantly fewer hospitalizations and lower mortality at 24 months follow-up.