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Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Prior Coronary Artery Bypass Graft Operation: A PARTNER Trial Subgroup Analysis

Friday, July 4, 2014

Submitted by

Mark Ferguson

Source

Source Name: Annals of Thoracic Surgery

Source URL: http://www.annalsthoracicsurgery.org/article/S0003-4975%2814%2900605-5/abstract

Author(s)

Kevin L. Greason, Verghese Mathew, Rakesh M. Suri, David R. Holmes, Charanjit S. Rihal, Tom McAndrew, Ke Xu, Michael Mack, John G. Webb, Augusto Pichard, Mathew Williams, Martin B. Leon, Lars Svensson, Vinod Thourani, Craig R. Smith

The PARTNER trial reported reduced mortality in pts with prior CABG who underwent surgical AVR compared to TAVR. This study further explores the 288 pts in these two groups. The groups were similar in their clinical presentation and had similar instances of procedure-related mortality, stroke, and MI. The TAVR pts had more paravalvular leak, at 2 years trended towards higher all-cause mortality, experienced more rehospitalizations, and had higher rates of mortality associated with death/rehospitalization and death/stroke. Outcomes in pts with prior CABG were better after surgical AVR than after TAVR, the causes for which are not completely understood.