Use of Hybrid Stage I to Stratify Between Single Ventricle Palliation and Biventricular Repair

This study explores the use of Hybrid Stage 1 Palliation (HS1P) in patients with congenital heart disease (CHD), particularly in those with single ventricle (SV) and biventricular (BiV) conditions. The researchers conducted a retrospective analysis of 39 patients who underwent HS1P, either with an expected BiV repair or an undetermined outcome. The results show that 68 percent of patients with anticipated BiV repair eventually underwent successful BiV repair, while 26 percent died before further intervention. Among patients with undetermined outcomes, 65 percent underwent BiV repair, and 30 percent had SV palliation. The study found that resolution of intracardiac risk factors (ICRF) was strongly linked to BiV repair success, while persistent ICRF correlated with SV palliation or death. Post-surgery complications and reinterventions were common, highlighting the high-risk nature of these patients. The study concludes that HS1P can be used to delay the decision between BiV repair and SV palliation, but mortality remains high, particularly for patients with marginal BiV potential.