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Journal and News Scan
October 17, 2019
Submitted by: Mark Ferguson
Patients with proton-pump inhibitor refractory heartburn have a multitude of underlying causes. In this randomized trial of patients with refractory heartburn, only 21% had symptoms related to gastroesophageal reflux disease. Treatments included fundoplication vs omeprazole and baclofen vs omeprazole. Success at one year was higher in the surgery group than either of the medical therapy groups (67% vs 28% vs 12%).
October 15, 2019
Submitted by: Mark Ferguson
Using gender specific thresholds for abnormalities in cardiac troponin I, the rate of injury among women increased by 42%. This did not translate into improved management of women, who remained about half as likely to undergo revascularization, receive dual antiplatet therapy, or undergo other interventions.
October 14, 2019
Submitted by: Aristotle Protopapas
A narrative review offering an intensivists' viewpoint on specific cardiovascular sequela of double-lumen anaesthesia for pulmonary resections (and by extension, implantation of donor lungs) and other cardiothoracic and vascular operations.
October 14, 2019
Submitted by: Aristotle Protopapas
An extremely interesting research question abutting cardiac physiology, and a manuscript that may generate future additional clinical research.
October 14, 2019
Submitted by: Aristotle Protopapas
Interesting sizeable series, and a commentary that follows, on what is effectively a thoracic example of Natural Orifice Transluminal Endoscopic Surgery (NOTES).
October 12, 2019
Submitted by: Joel Dunning
These incredible findings are the result of an analysis of the New York State Department of Health Statewide Planning and Research Cooperative database. They represent over 99,000 major lung resections from 1995 to 2014. Surgeons performing more than 30 lobectomies per year have a mortality of 1% and surgeons performing less than 12 per year have a mortality of 2.8%. But the most surprising fact is that the low-volume surgeons performed 90% of the lobectomies. Do you agree with the results of this very large study and if you do, what do you think should happen about this?
October 12, 2019
Submitted by: Mark Ferguson
The association of cardiovascular events and all-cause mortality with optimism was assessed in this meta-analysis. Optimism was associated with a decreased risk of cardiovascular events (ROR 0.65) and a decrease in all-cause mortality (RR 0.86). Mechansims have yet to be identified.
October 12, 2019
Submitted by: Tom C. Nguyen
Excellent document from the EACTS, STS, and AATS emphasizing the importance of standardization of prosthetic heart valve labeling.
October 11, 2019
Submitted by: Benjamin Bidstrup
This timely review examines the use of single and mutiple agents to decrease saphenous graft failure after CABG. These are difficult and expensive studies to perform, requiring repeat imaging after surgery, a procedure patients are often reluctant to undergo. In this analysis, the use of aspirin remains the lynchpin, with ticagrelor and clopidigrel as second agents improving outcomes, albeit at an increased in risk of bleeding.
October 10, 2019
Submitted by: Mark Ferguson
Reporting of postmarket outcomes for the Sapien 3 and Mitraclip devices frequently misclassified patient deaths as device malfunction or other outcomes. Misclassification for Sapien 3 involved 17.5% of patient deaths, and involved 24.7% of patient deaths for Mitraclip. These outcomes are important for the public and physicians to understand when discussing risks and benefits of such devices.