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Basic Science

May 30, 2024
This paper details an under-development animal model to study the vascular pathology of vein grafts in a variation of the initial Carrel canine bypass experiment. The possible findings on detrimental effects of hydrostatic distention, if and when quantified, may alter surgeons’ harvesting techniques.
November 6, 2023
An elegant and surprisingly easily read cohort study of mechanical destruction of platelets in ECMO circuits that parallels what we already know in pumps for full cardiopulmonary bypass. The authors propose a biomarker as a target for thrombotic modulation .
August 31, 2023
An open access genomic study of carotid atheroma : when should we offer revascularisation?
August 7, 2023
In a research letter on a small pilot genomic study of sampling coronary atheroma, the authors offer a brief explanation on how their technique can be applied to detect stability of coronary plaque.
September 20, 2022
Plasma metabolomic profiles were examined to determine differences in social determinants of health between Black and white women. This observational study paves the groundwork for further investigation of social disparity in atheromatous disease.
July 11, 2022
There could be some translational value for cardiovascular surgical practice from this prospective cardiovascular health study. The mechanistic link warrants further investigation and interpretation.
June 23, 2022
This scientific statement is a granular contribution to a major cardiovascular issue, illuminating nuances of the "generally recognized as safe" (GRAS) FDA designation. One would expect the relevant Thoracic Associations in North America and Europe to contribute to this debate.
May 26, 2022
No statistical significance ,between the two arms, regarding the OVERALL survival in this RCT funded by the supplier and manufacturer of the immunotherapy in question....
May 18, 2022
Gripping vignette of a fatal case of renocardiac pathologies. The stills from the (sadly non-contrast) CTA are most interesting.
April 5, 2022
A brief but comprehensive editorial on nuances of the links between atrial fibrillation and heart failure, apropos a trial we have commented recently on, by the Johns Hopkins team that develops the calmodulin-dependent protein kinase II inhibitor molecules   

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