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Early Injury Landscape in Vein Harvest by Single-Cell and Spatial Transcriptomics

Thursday, May 30, 2024

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Author(s)

Marina E. Michaud, Lucas Mota, Mojtaba Bakhtiari, Beena E. Thomas, John Tomeo, William Pilcher, Mauricio Contreras, Christiane Ferran, Swati Bhasin, Leena Pradhan-Nabzdyk, Frank W. LoGerfo, Patric Liang and Manoj K. Bhasin

This paper details an under-development animal model to study the vascular pathology of vein grafts in a variation of the initial Carrel canine bypass experiment. The possible findings on detrimental effects of hydrostatic distention, if and when quantified, may alter surgeons’ harvesting techniques.

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