This article presents findings from the second-ever pig-to-human heart xenotransplant. A 58-year-old patient with end-stage heart failure received a 10-gene-edited porcine heart and was maintained on a novel anti-CD40L immunosuppressive regimen.
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Transplantation
February 20, 2025
This retrospective single-center study evaluates the outcomes of isolated single lung transplants (SLT) (one usable, one declined lung) compared to split SLTs (both lungs are used for different recipients). Approximately 80 percent of lung transplants are bilateral, leading to a paucity of literature on isolated SLT outcomes.
February 20, 2025
This group presents a standardized, step-by-step technique for robotic-assisted lung transplantation. The authors describe port placement strategies, dissection techniques, and sequential anastomosis to optimize surgical precision while minimizing trauma.
February 13, 2025
Researchers have shown that patches of muscle grown from stem cells can help repair a failing heart. A laboratory-grown biological transplant with the potential to stabilize and strengthen the heart muscle can be implanted onto the heart surface.
January 9, 2025
This study investigates lung transplant outcomes across age groups, highlighting key survival trends and risk factors. Among the 33,644 recipients, older patients (aged 65–79 years) more frequently underwent single lung transplantation.
December 27, 2024
The article evaluates the outcomes of a paradigm shift in lung transplantation. Traditionally, the lung with the lowest perfusion was implanted first to minimize intraoperative hemodynamic instability.
December 12, 2024
In the TRISCEND II trial, a total of 400 patients with severe symptomatic tricuspid regurgitation were randomized in a 2:1 ratio to undergo either transcatheter tricuspid valve replacement with medical therapy (valve-replacement group) or medical therapy alone (control group).
October 31, 2024
The role of transcatheter aortic valve replacement (TAVR) for the treatment of aortic stenosis in the pre- and post-lung transplant population is limited. This specific patient population is considered high risk for general anesthesia and for surgical aortic valve replacement.
January 23, 2024
Interesting conclusion on superiority of CRT over ICD
July 20, 2023
This study aimed to determine if socioeconomic status and region had any effect on post-transplant outcomes across different races and ethnicities. After another study found that transplant outcomes varied greatly based on multiple factors, researchers wanted to know if socioeconomic factors played into differences based on race.