This instructive paper includes three separate meta-analyses focusing on patient-prosthesis mismatch (PPM) after TAVR. These meta-analyses revealed the following:
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Catheter-Based Treatments
September 23, 2015
The authors conducted a propensity-matched analysis of outcomes and costs associated with TAVR vs. SAVR procedures in patients considered either intermediate risk (STS PROM 4-8%) or high risk (STS PROM >8%) within the Commonwealth of Virginia.
August 3, 2015
In this manuscript the authors describe their findings in a retrospective review of prospectively obtained 5-year follow up data on 353 patients undergoing transcatheter aortic valve implantation (TAVI) with the CoreValve prosthesis in 8 Italian centres.Transfemoral access was used in 317 patients (89.8%); in the rest of the patients in whom the tran
June 19, 2015
The FDA approved Edwards' Sapien third generation transcatheter aortic valve, designed to limit paravalvular leakage by incorporating a skirt at the base of the valve. The approval was based on results of the PARTNER II S3 study, which demonstrated improved rates of paravalvular leakage at 30 days (<4%) compared to 10% to 20% rates for other valv
June 17, 2015
In this paper the authors report on the 2-year results of the randomized US pivotal trial for surgical and self-expanding percutaneous aortic prosthetic valves. The survival benefit observed at 1 year in the transcatheter group were sustained at two years.
June 14, 2015
In this manuscript the authors report on data from the German Aortic Valve Registry (GARY) comprising 15964 transcatheter aortic valve replacement (TAVR) procedures performed from 2011 to 2013 evaluating severe vital complications (SVCs), technical complications of the procedures (TCOs), other complications, conversion to sternotomy and in-hospital d
June 13, 2015
In this open-access article, the authors describe their findings in a systematic review of transcatheter heart valve (THV) failures, comprising 70 articles and 87 individual cases. Unusual complications such as late embolization (mostly into the left ventricle) and prosthetic compression (exclusively in balloon expandable THVs) are described.
April 24, 2015
In this manuscript the authors describe a systematic review of 71 cases of transcatheter heart valve embolization. In 72% of the patients, the prosthesis used was a balloon expandable one. In most cases valve embolization occurred soon after implantation and it happened in the aortic direction.
December 30, 2014
This is a retrospective review of 260 patients undergoing TAVI, looking at the relationship between aortic valve calcium score and post procedural paravalvular leakage. The results suggest that the amount of calcification significantly impacts the occurrence, the degree and localization of paravalvular leakage after TAVI.
June 26, 2014
In this study the authors use data from 1432 patients included in the German TAVI registry to identify variables which predict poor outcome in patients left with more than mild aortic regurgitation (AR) following TAVI. The Medtronic Core Valve prosthesis had been used in the great majority of the procedures.