What effect has the SYNTAX trial had on practice in Europe? Philippe Kolh reviews the trial and its guidelines.
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Coronary Disease - PCI
June 11, 2016
The authors compare single-institution retrospective data on outcomes of coronary bypass grafting or PCI for isolated CAD in over 12,000 pts. Overall survival was better for PCI patients (46% vs 34% at 15 yrs). However, survival for patients undergoing CABG with multiple arterial grafts was superior to most other interventions at 15 years and was s
April 3, 2016
In a propensity-matched analysis, Rosenblum and colleagues found that hybrid revascularization as compared with coronary artery bypass grafting with either single or bilateral internal mammary artery grafts was superior in terms of secondary short-term outcomes (e.g.
March 29, 2016
Joseph Sabik of the Cleveland Clinic, Cleveland, Ohio, considers whether the SYNTAX trial changed cardiology and cardiothoracic surgery practice in the United States.
March 23, 2016
Guidelines recommend that ICDs should not be implanted until after 90 days following revascularization in patients with an EF<35% and an MI. Studies have shown that no clinical benefit or detriment was derived by implantation prior to 90 days.
March 11, 2016
The authors provide an excellent overview of the rationale for screening all patients with a new diagnosis of cardiomyopathy for coronary artery disease. This rationale includes the following:
January 23, 2016
In an analysis from the SYNTAX trial that randomized PCI vs CABG in patients with complex coronary disease, Milojevic et al found that patients had significantly higher rates of cardiac death after PCI, which was particularly caused by significantly higher rates of myocardial infarction-related death.
November 17, 2015
The authors report on the extended follow-up of Courage Trial patients for up to 15 years. In this trial, patients with chronic stable angina were randomized to medical therapy alone versus PCI plus medical therapy. At extended follow-up, there was no difference in overall survival between the two treatment strategies.
September 24, 2015
The investigators of this study compared survival of bare metal stent percutaneous coronary intervention (BMS-PCI) versus drug-eluting stent PCI (DES-PCI) versus single artery CABG (SA-CABG) versus multiarterial CABG (MA-CABG) in patients with multivessel coronary artery disease.
July 20, 2015
The authors of this paper investigated the outcomes of percutaneous coronary intervention (PCI) performed in centers with and without cardiac surgical support onsite in a large database in the United Kingdom between 2006 and 2012. They found in multivarate analysis that there was no difference at 30 days, 1 year or 5 years.