In this manuscript, the authors use meta-analysis techniques to evaluate the relationship between measured coronary fractional flow reserve (FFR) and patients’ outcomes.
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Coronary Disease - PCI
October 19, 2014
September 5, 2014
This controlled randomized trial examined the benefits of targeted PCI vs medical therapy alone for patients with stable CAD and stenosis who were found to have zones of fractional flow reserve of less than 0.8 at angiography. Patients without regions of FFR <0.8 were entered into a registry. The composite outcome was death, nonfatal MI, or urg
August 18, 2014
The study aims to compare outcomes between minimally invasive coronary artery bypass (MINI–CAB) and drug–eluting stent (DES) implantation for isolated left anterior descending (LAD) disease. Given the available evidence, MINI–CAB results in lower TVR rates, but otherwise similar clinical outcomes when compared with DES in patients with LAD disease.
August 8, 2014
In this study the cost-effectiveness of CABG vs. DES-PCI was analysed from a U.S. Healthcare perspective. Using 5-year cost and quality-of-life data from the SYNTAX trial and lifetime extrapolations, the authors found that CABG was an economically attractive treatment option for most patients with 3-VD or left main CAD disease.
June 18, 2014
Coronary artery bypass grafting versus drug-eluting stents in patients with severe coronary artery disease and diabetes mellitus: a systematic review and meta-analysis Journal of Diabetes, 06/11/2014 Evidence Based Medicine Review Article
June 4, 2014
Coronary artery bypass grafting (CABG) has been considered the standard of care for patients with three-vessel disease (3VD), but long-term comparative results from randomized trials of CABG vs. percutaneous coronary intervention (PCI) using drug-eluting stents (DES) remain limited.
May 29, 2014
This study assessed nonfatal outcomes comparing CABG to PCI for pts with multivessel CAD identified in national registries. The outcome was the composite of death, MI, or stroke. Registry data were linked to Medicare data to obtain outcomes and pts were propensity score matched. The authors identified a total of 86,244 CABG and 103,549 PCI pts. A
April 24, 2014
This article compares clinical adverse events after percutaneous intervention with drug‐eluting stents (DESs) and coronary artery bypass grafting (CABG) in patients with ESRD. Early mortality is lower with DESs compared with coronary artery bypass in patients with ESRD. Rate of reintervention is significantly higher in the DES cohort.
April 16, 2014
Ischaemic heart disease is a major risk factor for heart failure. However, long–term benefit of percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) in those patients has not been well elucidated.
April 13, 2014
This manuscript reports on the 5-year outcomes in the 705 patients with left main (LM) lesions enrolled in the randomized arm of the SYNTAX trial. Follow-up data to 5 years were available in 96.9% of patients who underwent PCI and 92.5% of patients randomized to CABG.