This randomized trial (NEAT-HFpEF) of 110 subjects (59 placebos) disproves, by clinical and biological markers, the utility of nitrates for exercise tolerance. This is a subset of cardiac failure patients we are likely to encounter in general cardiothoracic surgical practice.
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Pharmacology
May 28, 2014
The distribution of sympathetic and parasympathetic nerve fibres of the epicardial subplexuses at the heart hilum was elucidated. The results may help to explain mechanisms of the initiation of supraventricular arrhythmias and to determine effective treatment options.