In this phase three national, multicenter, UK randomized controlled trial, the authors seek to compare outcomes after extended pleurectomy decortication plus chemotherapy versus chemotherapy alone. The trial recruited patients between 2015 and 2021 from 26 UK hospitals, recruiting and randomly assigning patients with a 1:1 allocation ratio.
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Pleura - Mesothelioma
December 6, 2023
CTSNet Editor in Chief Joel Dunning spoke with Dr. David Waller about the MARS-2 mesothelioma clinical trial. They discussed various discrepancies in the trial that make it difficult to apply to real-world mesothelioma treatment.
October 25, 2023
This video demonstrates an extended pleurectomy and decortication, which is a cytoreductive procedure for the surgical management of malignant pleural mesothelioma.
January 12, 2023
A recent study found that mesothelioma patients who undergo both lung-sparing extended pleurectomy and decortication can achieve extended survival compared to those who undergo just one type of surgery.
May 24, 2019
Patient Care and General Interest
Despite being the leading cause of death in the US, heart disease was the most-Googled disease in only one state: Maine.
July 27, 2018
A useful editorial debating current issues on the classification of mesothelioma.
July 19, 2018
Filmed at the 2018 STS Annual Meeting in Ft Lauderdale, FL, Joel Dunning of the James Cook University Hospital in London, UK, interviews Raja Flores of the Mount Sinai School of Medicine in New York, USA, about surgical treatment for mesothelioma and lung cancer.
February 1, 2018
Apostolos Nakas of the Glenfield Hospital in Leicester, UK, presents an overview of the surgical treatment of mesothelioma.
December 13, 2017
As many will recall, world chess champion Garry Kasparov was defeated by IBM's Deep Blue computer in 1997. Now machine-learning algorithms have bested trained pathologists in differentiating between benign and malignant changes in sentinel lymph nodes in breast cancer patients. We can expect to see increasing involvement of AI in pathology as well
October 31, 2017
In this single institution study, the prognostic role of soluble mesothelin-related peptides (SMRP) was evaluated in patients with pleural mesothelioma. Preoperative levels of SMRP were related to tumor volume and disease-free survival. Percent change in postoperative SMRP was predictive of tumor recurrence.