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Accuracy of FDG-PET to Diagnose Lung Cancer in Areas With Infectious Lung Disease

Thursday, September 25, 2014

Submitted by

Mark Ferguson

Source

Source Name: JAMA

Source URL: http://jama.jamanetwork.com/article.aspx?articleID=1906615&utm_source=Silverchai…

Author(s)

Stephen A. Deppen; Jeffrey D. Blume; Clark D. Kensinger; Ashley M. Morgan; Melinda C. Aldrich; Pierre P. Massion; Ronald C. Walker; Melissa L. McPheeters; Joe B. Putnam Jr; Eric L. Grogan

This meta-analysis of 70 studies evaluated the utility of PET in assessing over 8,511 lung nodules, comparing regions in which infectious lung disease is endemic to other regions. Specificity was lower in regions with endemic infectious diseases, 61% vs 77%. Overall, the accuracy of PET was extremely heterogeneous.